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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSHZ2
All Species:
18.18
Human Site:
S433
Identified Species:
50
UniProt:
Q9NRE2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRE2
NP_775756.3
1034
115005
S433
V
E
K
M
Q
S
L
S
E
A
P
N
S
D
S
Chimpanzee
Pan troglodytes
XP_514730
1034
114957
S433
V
E
K
M
Q
S
L
S
E
A
P
N
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001097666
1037
115177
S436
V
E
K
M
Q
S
L
S
E
A
P
N
S
D
S
Dog
Lupus familis
XP_543057
1155
127934
S554
V
E
K
M
Q
S
Q
S
D
T
P
N
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q68FE9
1030
114204
L433
A
V
E
K
M
Q
S
L
S
E
T
P
N
S
E
Rat
Rattus norvegicus
XP_001074194
1033
114566
L436
A
V
E
K
M
Q
S
L
S
E
S
P
N
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509428
1037
115085
S438
V
E
K
M
Q
T
L
S
E
P
P
A
S
E
I
Chicken
Gallus gallus
XP_417506
1036
115062
E434
E
K
M
Q
S
L
S
E
A
P
A
S
D
S
P
Frog
Xenopus laevis
NP_001165937
1077
118777
S469
V
L
E
E
K
I
Q
S
I
P
L
P
P
T
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
81.7
N.A.
90.4
88.6
N.A.
85.5
84
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
97.4
84.6
N.A.
94.3
93.6
N.A.
91.3
90.1
64.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
0
0
N.A.
66.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
13.3
13.3
N.A.
80
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
0
0
0
0
12
34
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
12
45
0
% D
% Glu:
12
56
34
12
0
0
0
12
45
23
0
0
0
12
23
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
12
% I
% Lys:
0
12
56
23
12
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
12
45
23
0
0
12
0
0
0
0
% L
% Met:
0
0
12
56
23
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
45
23
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
34
56
34
12
0
12
% P
% Gln:
0
0
0
12
56
23
23
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
12
45
34
67
23
0
12
12
56
34
45
% S
% Thr:
0
0
0
0
0
12
0
0
0
12
12
0
0
12
12
% T
% Val:
67
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _